PSTC
News & Events
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May 22, 2017
miR-122 An Exploratory Biomarker of Liver Injury: An Industry Perspective on the State of the Science and Experiences Pre-Clinically and Clinically
The Critical Path Institute’s Predictive Safety Testing Consortium (PSTC) hosted a webinar focused on providing an industry perspective on the state of the science and preclinical and clinical experiences with mi-R122. This webinar was hosted by PSTC’s Hepatoxicity Working Group. The first presentation discussed the current state of miR-122 as a safety biomarker of liver...... -
May 26, 2016 - July 14, 2016
Current trends in BSEP inhibition and perturbation to bile acid homeostasis as mechanisms of drug-induced liver injury
The Critical Path Institute’s Predictive Safety Testing Consortium hosted a webinar series focused on BSEP inhibition and perturbation to bile acid homeostasis as mechanisms of drug-induced liver injury. Over the course of six two-hour webinars, scientists presented current data and research on clinical examples of BSEP inhibition and hepatotoxicity, in vivo tools for confirming perturbation......