Drug-Induced Liver Injury (DILI) Conference XVII
Asymmetry of Drug Safety and Efficacy in Clinical Trials with DILI- Toward Quantitative Estimate of Net Benefit to Patients
June 6, 2017 – June 7, 2017
College Park Marriott Hotel and Conference Center
Paul Watkins, Mark Avigan, John-Michael Sauer, Arie Regev, Gyongyi Szabo, John Senior
Drug-induced liver injury (DILI) is a major problem for drug development and clinical care. Several unresolved problems require new understanding and consensus. Especially difficult is much greater costs of adequate safety studies than for the proof of efficacy. This international academic-industry-government conference will discuss current findings and thinking on DILI and drug safety by expert hepatology, toxicology and special presentations. We encourage you to register, come, participate, and debate the issues for development of new agreements and guidance.
Tuesday, 6 June 2017
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7:30-8:00 am |
Continental Breakfast: outside the conference room; Register |
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8:00-8:30 am |
Opening Remarks Sweet and Sour DILI Keynotes: John Senior |
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8:30-11:30 am |
SESSION I: Best Practices in Clinical Drug Development Moderators: Arie Regev and Naga Chalasani |
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11:30–12:30 pm |
Lunch break |
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12:30 – 5:00 pm |
SESSION II: Evaluating DILI Signals in Clinical Trials to Inform Benefits, Risks Moderators: Michael Aleo and Mark Avigan |
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2:40 pm |
Refreshment Break |
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5:00 pm |
Reception: wine and hors d’oeurves; mingle, chat, and relax – dinner on your own |
Wednesday, 7 June 2017
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7:30-8:00 am |
Continental Breakfast |
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8:00-12 pm |
SESSION III: New Tools for Detection and Assessment of DILI Moderators: John-Michael Sauer and Neil Kaplowitz |
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9:40 am |
Coffee Break |
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12:00-1:00 pm |
Lunch break |
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1:00 – 5:00 pm |
SESSION IV: Consortia for Best Practices to Reduce DILI Moderators: Paul Watkins and Gyongyi Szabo |
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3:10 pm |
Refreshment Break |
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5:00 pm |
Adjourn |
Copies of slides shown and transcripts of speakers’ comments and discussions will be posted four weeks after the conference at: www.aasld.org. Events and Professional Development, Drug-Induced Liver Injury Conferences. Previous conference agendas, slides, and comments may be seen at the same site.
