News & Events
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January 1, 2018
Individual serum bile acid profiling in rats aids in human risk assessment of drug-induced liver injury due to BSEP inhibition
Cepa, Steven, David Potter, Lisa Wong, Leah Schutt, Jacqueline Tarrant, Jodie Pang, Xiaolin Zhang, et al. “Individual Serum Bile Acid Profiling in Rats Aids in Human Risk Assessment of Drug-Induced Liver Injury Due to BSEP Inhibition.” Toxicology and Applied Pharmacology 338 (01 2018): 204–13.
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November 22, 2017
What Evidence Do We Need for Biomarker Qualification?
Leptak C, Menetski JP, Wagner JA, Aubrecht J, Brady L, Brumfield M, Chin WW, Hoffmann S, Kelloff G, Lavezzari G, Ranganathan R, Sauer JM, Sistare FD, Zabka T, Wholley D. What Evidence Do We Need for Biomarker Qualification? Science Translational Medicine. 2017 Nov 22;9(417).
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April 1, 2017
Response of Novel Skeletal Muscle Biomarkers in Dogs to Drug-Induced Skeletal Muscle Injury or Sustained Endurance Exercise
Vlasakova, Katerina, Pamela Lane, Laura Michna, Nagaraja Muniappa, Frank D. Sistare, and Warren E. Glaab. “Response of Novel Skeletal Muscle Biomarkers in Dogs to Drug-Induced Skeletal Muscle Injury or Sustained Endurance Exercise.” Toxicological Sciences: An Official Journal of the Society of Toxicology 156, no. 2 (April 1, 2017): 422–27.
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January 1, 2017
Perspectives on using a multiplex human kidney safety biomarker panel to detect cisplatin-induced tubular toxicity in male and female Cynomolgus monkeys
Chen, Yafei, J. Dale Thurman, Lewis B. Kinter, Russell Bialecki, and J. Eric McDuffie. “Perspectives on Using a Multiplex Human Kidney Safety Biomarker Panel to Detect Cisplatin-Induced Tubular Toxicity in Male and Female Cynomolgus Monkeys.” Toxicology and Applied Pharmacology 336 (01 2017): 66–74
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January 1, 2017
Preclinical Biomarker Qualification
Sauer JM, Porter AC, Biomarker Programs, Predictive Safety Testing Consortium. Preclinical Biomarker Qualification. Experimental Biology and Medicine (Maywood, NJ). 2017 Jan 1.