News & Events

• February 23, 2019
  

  Investigating the Value of Urine Volume, Creatinine, and Cystatin C for Urinary Biomarkers Normalization for Drug Development Studies

  Adedeji, Adeyemi O., Tony Pourmohamad, Yafei Chen, Jennifer Burkey, Catherine J. Betts, Susan J. Bickerton, Manisha Sonee, and James E. McDuffie. “Investigating the Value of Urine Volume, Creatinine, and Cystatin C for Urinary Biomarkers Normalization for Drug Development Studies.” International Journal of Toxicology 38, no. 1 (February 2019): 12–22.

• December 1, 2018
  

  Brief Overview: Assessment of Compound-induced Acute Kidney Injury Using Animal Models, Biomarkers, and In Vitro Platforms

  McDuffie, James E. “Brief Overview: Assessment of Compound-Induced Acute Kidney Injury Using Animal Models, Biomarkers, and In Vitro Platforms.” Toxicologic Pathology 46, no. 8 (December 2018): 978–90.

• November 1, 2018
  

  Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective

  Kenna, J. Gerry, Kunal S. Taskar, Christina Battista, David L. Bourdet, Kim L.R. Brouwer, Kenneth R. Brouwer, David Dai, et al. “Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective.” Clinical Pharmacology and Therapeutics104, no. 5 (November 2018): 916–32.

• January 22, 2018
  

  Candidate biomarkers for the diagnosis and prognosis of drug-induced liver injury: An international collaborative effort

  Church RJ, Kullak-Ublick GA, Aubrecht J, Bonkovsky HL, Chalasani N, Fontana RJ, et al. Candidate biomarkers for the diagnosis and prognosis of drug-induced liver injury: An international collaborative effort. Hepatology. 2018 Jan 22.

• January 1, 2018
  

  Performance Assessment of New Urinary Translational Safety Biomarkers of Drug-induced Renal Tubular Injury in Tenofovir-treated Cynomolgus Monkeys and Beagle Dogs

  Gu, Yi-Zhong, Katerina Vlasakova, Sean P. Troth, Robert L. Peiffer, Herve Tournade, Flavia R. Pasello Dos Santos, Warren E. Glaab, and Frank D. Sistare. “Performance Assessment of New Urinary Translational Safety Biomarkers of Drug-Induced Renal Tubular Injury in Tenofovir-Treated Cynomolgus Monkeys and Beagle Dogs.” Toxicologic Pathology, January 1, 2018, 192623318775023..